Use a physical home office space and designate it as such.
Look for an area in your house that you can use as a home office. Make sure this is the area that can offer the most privacy and quiet. Avoid rooms such as the Family activity room, den or your bedroom. High-traffic rooms are not only impractical, they also show you're inconsiderate. You're not the only one living in the house, remember?

Next, add a physical barrier to make sure it is separate from the rest of the house. Build a wall or just some temporary barriers. You'll avoid a strain in family relationships by making sure your home office is treated and respected as a place for business, not an extra play or study area.

Use separate facilities.
The most common source of strain in family relationships when there's someone working from home involves the use of facilities like phone lines and other equipment. Subscribe to a separate phone line for your home business. That way, all your calls will be made and directed to a dedicated line, inaccessible to other family members. Having your own computer will also help so no one has to sneak in to borrow it for a school assignment or to chat with friends.

Schedule some family time.
Your family will always need your attention. To avoid strain in your relationship, try to set aside a few hours each day (early morning, lunch or at night) for family time. Your family will try to understand your work but it will be tough for them, seeing you physically present but unavailable. If the pressure is too much, consider hiring help. That will take your mind off the daily home stuff while you focus on working from home.